Current Studies

Research findings from the laboratory are used to improve our understanding of musculoskeletal and neuromuscular disorders, as well as develop new treatment approaches. To find more information on a particular research study, please view the outlines and general eligibility criteria below. If you are interested in taking part in a research study in the lab, please click the respective study links below.

1) Linking biomechanical and imaging outcomes to better understand the effects of running on knee joint health

Participants Needed

Overview: Physical activity has been widely recognized as an important treatment approach for knee osteoarthritis (OA); however, little is known about the effects of running with this condition. Previous studies have suggested healthy knee cartilage has the ability to become stronger immediately after running in the short-term, but it remains unclear if unhealthy knee cartilage would react the same.

Objectives: To investigate the effects of running on individuals with knee osteoarthritis, including response of cartilage immediately following a run, as well as following a 12-week running program increasing running volume.

For more information about participating in this study and to register your interest, click here.

2) Foot progression angle modification: an exploratory six-week intervention in people with knee osteoarthritis

Participants Needed

Overview: An emerging strategy to manage knee osteoarthritis is to change walking motions to lower knee joint loads. Changing the position of the foot while walking has been shown to lower knee joint loads and improve symptoms, but it is unclear if patients can learn these modifications and if they can be performed outside of the laboratory.

Objectives: To investigate the progression of learning a walking modification over six weeks and the differences between two approaches to instruct the walking modification.

For more information about participating in this study and to register your interest, click here.

3) Shoe-worn Orthotic Insole Treatment and Knee Osteoarthritis

Participants Needed

Overview: One form of conservative treatment for managing knee osteoarthritis is to modify knee joint loading with lateral wedge insoles. However, the change in knee joint loads while wearing lateral wedge insoles can vary between people due to individual differences in foot and lower limb alignment. Quantifying these differences in individual characteristics may help with predicting which people with knee osteoarthritis may be best suited for this type of treatment. Moreover, little is known about how the knee joint interface changes with lateral wedge insole use.

Objectives: To identify predictors of change in knee joint loads while walking and to assess how the knee joint interface changes with lateral wedge insole wear in individuals with knee osteoarthritis.

For more information about participating in this study and to register your interest, click here.

4) Gait Modification Combined with Lateral Wedge Insoles for the Treatment of Knee Osteoarthritis

Participants Needed

Overview: A primary risk factor for the structural progression of knee osteoarthritis is excessive or abnormally distributed knee joint load during walking. This study will examine the combined effects of two conservative treatment strategies (lateral wedge insoles and gait modification) to redistribute loading of the knee joint. The gait modification training will be administered with and without the help of a smart shoe training aid providing vibration-based feedback during walking.

Objectives: To examine knee and ankle joint biomechanics when walking with a change in foot motion, a lateral wedge insole, or a combination of the two, and to examine the ease of teaching a change in foot motion using vibration-based feedback.

For more information about participating in this study and to register your interest, click here.